Research Funding Opportunities

2020 Request for Applications (RFA):
International Research Grants in Congenital Muscular Dystrophy
Application Deadline: Friday, 07 February 2020, 11:59 pm (local time)
Thanks to the ongoing dedication and support of the CMD community, we are pleased to announce the availability of research funding for each of the five CMD subtypes listed below.

Each CMD subtype constitutes one competing application for a research award, independent of other CMD subtypes.

2020 Funding Opportunities

LMNA: Up to $50,000 in Funding for Up to Two Years (max $50k per grant)


Purpose: Promote the discovery of underlying disease mechanisms and the preclinical development of potential therapies, as well as the clinical translation of those efforts. As cardiac issues are the most hunting fear for patients and families we are particularly interested in receiving applications focused on testing potential therapies for LMNA-related cardiac pathologies.

Areas of Interest: Including but not limited to, 1) unraveling pathways involved in skeletal muscle or cardiac muscle pathology, 2) identifying novel drug targets or gene therapies, and 3) testing new strategies to treat disease or any of its incapacitating consequences (e.g. contractures, respiratory function decline, etc).

We will also accept applications proposing to create or improve disease models (e.g. animal models, patient-derived cell models), and encourage applications on biomarker discovery or functional outcome measures to assess therapeutic impact in an effort to bring LMNA-CMD closer to Clinical Trial Readiness.




Collagen VI: Up to $50,000 in Funding for Up to Two Years (max $50k per grant)


Purpose: Promote the discovery of underlying disease mechanisms and the preclinical development of potential therapies, as well as the clinical translation of those efforts.

Areas of Interest: Including but not limited to, 1) understanding the cause of disease, 2) understanding tissue-specific phenotypes, 3) unraveling pathways involved in disease, 4) identifying novel drug targets or gene therapies, and 5) testing new strategies to treat disease or any of its incapacitating consequences (e.g. contractures, respiratory function decline).

We will also accept applications proposing to create or improve disease models (e.g. animal models, patient-derived cell models), and encourage applications on biomarker discovery or functional outcome measures to assess therapeutic impact in an effort to bring COL6-CMD closer to Clinical Trial Readiness.




LAMA2: Up to $50,000 in Funding for Up to Two Years (max $50k per grant)


Purpose: Promote the discovery of underlying disease mechanisms and preclinical development of potential therapies, as well as the clinical translation of those efforts.

Areas of Interest: Including but not limited to, 1) understanding the cause of disease, 2) unraveling pathways involved in disease, 3) identifying novel drug targets or gene therapies, and 4) testing new strategies to treat disease or any of its detrimental consequences (e.g. fibrosis, seizures, contractures, respiratory function decline).

We also encourage applications on biomarker discovery or functional outcome measures to assess therapeutic impact in an effort to bring LAMA2-CMD closer to Clinical Trial Readiness.




SELENON: Up to $50,000 in Funding for Up to Two Years (max $50k per grant)


Purpose: Promote the discovery of underlying disease mechanisms and preclinical development of potential therapies, as well as the clinical translation of those efforts.

Areas of Interest: Including but not limited to, 1) understanding the cause of disease, 2) unraveling pathways involved in disease, 3) identifying novel drug targets or gene therapies, and 4) testing new strategies to treat disease or any of its incapacitating consequences (e.g. contractures, respiratory function decline).

We will also accept applications proposing to create or improve disease models (e.g. animal models, patient-derived cell models), and encourage applications on biomarker discovery or functional outcome measures to assess therapeutic impact in an effort to bring SELENON-RM closer to Clinical Trial Readiness.





Application Information

Eligibility


This opportunity is open to all international researchers who hold a minimum academic position of Assistant Professor or equivalent, and maintain an institutional contract that extends beyond the duration of the proposed grant period.

If you are currently executing a previously funded Cure CMD project or have been funded by Cure CMD in the past, you must complete all outstanding contractual requirements (ie. final reports), but you may still apply. In these cases, please attach a progress report or final progress report (maximum 3 pages) to your application in order to maintain standing eligibility.




How to Apply


  1. Carefully review our 2020 Grant Guidelines
  2. Carefully review our 2020 Grant Policy
  3. Download and complete the 2020 Cure CMD Grant Application
  4. Upload your completed application or submit via email attachment to grants@curecmd.org
  5. Applications must be received on or before Friday, 07 February 2020, 11:59 pm local time




Application Review


All applications will be peer reviewed by Cure CMD's Scientific Director, members of our Scientific Advisory Board, and external reviewers as necessary. Applicant may be required to provide rebuttal to reviewer inquiries, or update certain aspects of their application based on reviewer recommendation in order to be considered for an award.

Grant awards will be announced on or before 31 May 2020.




Questions? Get in Touch


Please do not hesitate to get in touch with any questions or concerns you may have about our 2020 RFA!




Grant Period


Funding for awarded grants will begin July 1, 2020, pending completion of a fully executed agreement between the Principal Investigator, Associate Investigator(s), Awardee Institution's Financial Officer, and Cure CMD's Scientific Director and Executive Director. Please review our guidelines and policy for more information about how Cure CMD administers grant awards.





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