Cure CMD Co-Funds SEPN1 Research Project with AFM

Cure CMD (Congenital Muscular Dystrophy) is eager to announce a co-funded grant, in partnership with AFM-Téléthon, for Dr. Esther Zito’s research project, “Ablation of the Maladaptive ER-Stress Response to Improve Altered Calcium-Handling and Restore Diaphragm Function in SELENON Knock-Out Mice.” Cure CMD and AFM-Téléthon will award Dr. Zito $60,000 over two years. This is the second research project focused on SEPN1-CMD that Cure CMD is funding in 2018. Dr. Zito’s project is a “proof of principle” that removing or blocking specific enzymes which causes pathogenic oxidative stress and calcium leakage will restore the needed intramuscular calcium regulation for the normal contraction-relaxati

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